General Information

  • ID:  hor000344
  • Uniprot ID:  Q1DH34
  • Protein name:  Allatostatin 3
  • Gene name:  NA
  • Organism:  Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
  • Family:  Allatostatin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Stegomyia (subgenus), Aedes (genus), Aedini (tribe), Culicinae (subfamily), Culicidae (family), Culicoidea (superfamily), Culicomorpha (infraorder), Nematocera (suborder), Diptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  GO:0005184 neuropeptide hormone activity
  • GO BP:  GO:0007165 signal transduction
  • GO CC:  NA

Sequence Information

  • Sequence:  ASAYRYHFGL
  • Length:  10(157-166)
  • Propeptide:  MRPSTTPMVLLSYLAFVLCLACVAYGSSALGSSSGTSDQSLFGGGAGGGGGSASAESDIGDDRGQQEISQATFQHMLAVRSPKYNFGLGKRRYIIEDVPGAKRLPHYNFGLGKRARNNLLEYDDDSAPSWSEDYSSLIPRDGLDYDGDKDKSAEKRASAYRYHFGLGKRRVYDFGLGKRVYEDKRLPNRYNFGLGRR
  • Signal peptide:  MRPSTTPMVLLSYLAFVLCLACVAYGSSA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-Q1DH34-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor000344_AF2.pdbhor000344_ESM.pdb

Physical Information

Mass: 134503 Formula: C56H77N15O14
Absent amino acids: CDEIKMNPQTVW Common amino acids: AY
pI: 9.17 Basic residues: 2
Polar residues: 4 Hydrophobic residues: 4
Hydrophobicity: -13 Boman Index: -1080
Half-Life: 4.4 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 59
Instability Index: -1348 Extinction Coefficient cystines: 2980
Absorbance 280nm: 331.11

Literature

  • PubMed ID:  20163154
  • Title:  Neuropeptidomics of the Mosquito Aedes Aegypti